Pratika Yuhyi Hernanda was born on October 22, 1979, in Lumajang, East Java province, Indonesia. She grew up and attended elementary, middle, and high school in her hometown, Surabaya, East Java, Indonesia.

In 1997, she started her study of medicine at the Medical Faculty of Airlangga University, Surabaya Indonesia. Soon after her graduation in 2004, she worked at Wijaya Kusuma University, Faculty of Medicine, as a lecturer and also a researcher in the Laboratory of Medical Genetics and doing research in the field of medical genetics, especially on Down syndrome and Thalassemia, under the supervision of Prof. dr. S.M Soeatmadji. Then she took a study leave to enroll in the master program on Genetic Epidemiology, at the Department of Epidemiology, Erasmus Medical Centre Rotterdam, The Netherlands in 2007, which required 1 year of full-time study. She subsequently went back to Indonesia and continued her work as a lecturer and researcher at the same institution, and she retains a formal position there up till now. Highly motivated to succeed, in 2010 she did laboratory training abroad to do research on Thalassemia, at one of the best hemoglobinopathy centers in the world, the Hemoglobinopathy laboratory of Leiden University Medical Centre (LUMC), The Netherlands. Those experiences are truly indicative of her motivation for success.

In 2012, she started her Ph.D. program at the Department of Gastroenterology and Hepatology, Erasmus Medical Center Rotterdam, The Netherlands, to carry out research on liver cancer. Under the supervision of the remarkable professor Prof. Maikel .P Peppelenbosch and the sharp-minded, young-talented researcher Dr. Qiuwei Pan, she focused on the role of mesenchymal stromal cells and SMADs family in liver cancer. And now she continues her work in the Biomedical Department, Faculty of Medicine, Wijaya Kusuma University, as a lecturer and researcher on cancer genetics.