To live long, healthy and happy you must remain physically and intellectually active, avoid stress and anxiety, limit ultra-processed food, have a regular medical check to detect and treat any disease in a curable stage, and take a nutraceutical food supplement. The composition of the example nutraceutical QALY®, consisting of several minerals, plant extracts and vitamins, reduces the cardiovascular mortality by 40%, and decreases the risk of colorectal cancer by 30%. Together with healthy life style, the intake of the nutraceutical may prevent half of the cases of neurodegenerative diseases and dementia.